Does vincristine cause muscle weakness
In its more severe form, muscle weakness develops and is more pronounced in the distal muscles of the hands and feet. The early symptoms include numbness and tingling of the hands and feet, which is accompanied by loss of deep tendon reflexes.
Does vincristine cause leg pain
Convulsions, frequently associated with hypertension, have been reported in a small number of patients receiving vincristine sulfate. Pain in these areas may be severe. Jaw pain, pharyngeal pain, parotid gland pain, bone pain, back pain, limb pain, and myalgias have all been reported.
What is the side effects of vincristine
More common
- double or blurred vision
- having trouble walking.
- sagging eyelids
- headache.
- jaw ache
- tingling or numbness in the fingers and toes
- Fingers and toes are hurting.
- the testicles hurt.
What is the toxic side effect of vincristine
This medication may cause nausea, vomiting, weight loss, diarrhea, mouth sores, dizziness, or headache. It may also cause constipation, which in some cases may become serious; if any of these effects persist or worsen, contact your doctor or pharmacist right away.
What is vincristine neuropathy
Vincristine-induced motor neuropathy, which results from damage to peripheral nerves, is characterized by weakness in the upper and lower extremities and the development of wrist- or foot-drop. May 17, 2017
Why is vincristine being discontinued
“Teva decided to discontinue vincristine and alerted the FDA of its decision in March 2019 based on this lack of demand for the Teva product at the time, and to enable us to re-adjust our limited resources to make other life-saving products needed in the market.” Oct. 21, 2019
Does vincristine cause neuropathy
Although vincristine is an important chemotherapy drug used to treat pediatric acute lymphoblastic leukemia, some patients may develop severe peripheral neuropathy as a side effect.Jun 15, 2020
Does vincristine cause bone marrow suppression
Bone marrow suppression is a side effect of most chemotherapy drugs, including vincristine, and occurs when the bone marrow is unable to produce enough red blood cells, white blood cells, or platelets to meet demand.
Why is vincristine an effective chemotherapy drug
Vincristine is a chemotherapy drug that belongs to a class of medications known as vinca alkaloids. It functions by preventing the cancer cells from dividing into two new cells, thereby halting the growth of the cancer.
What are the side effects of rituximab
Side Effects
- back ache
- Tarry, dark stools.
- swelling or bloating of the face, hands, arms, feet, or lower legs.
- blood in the stools or urine.
- body pain or aches.
- skin irritation or burning
- or tightness in the chest.
- having trouble breathing
Are vincristine side effects permanent
Potential Post-Treatment Side Effects Some patients may experience post-treatment side effects that last months or years after the treatment has ended.
Does vincristine cause cardiotoxicity
As a cardiotoxic substance, vincristine can lead to ischemic heart disease.
What class of drug is vincristine
Vincristine belongs to the group of drugs known as vinca alkaloids.
What are the side effects of dexamethasone
Dexamethasone may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
- stomach ache
- stomach discomfort
- vomiting.
- headache.
- dizziness.
- insomnia.
- restlessness.
- depression.
Can vincristine cause pancreatitis
In our study, 2 patients who were receiving vincristine plus L-asparaginase developed mild pancreatitis. These patients were receiving vinca alkaloids and L-asparaginase therapy, which has been linked to pancreatitis in humans [23].
How much does vincristine cost
The typical retail price for Vincristine Sulfate, which belongs to the Mitotic Inhibitors class of medications, is $29.85 per 2, 2ML of 1MG/ML Solution, but you can pay just $1.92 with your SingleCare prescription drug discount card when using the Vincristine Sulfate coupon.
Does vincristine cause neutropenia
When used in multidrug chemotherapy protocols, vincristine has a negative side effect called neutropenia.
Does vincristine cause hyponatremia
The chemotherapy drugs most frequently linked to hyponatremia are vincristine, vinblastine, cisplatin, and cyclophosphamide.