Asked By: Brian Perry Date: created: Jun 28 2022
Which one of the following is antimetabolite drug
Answered By: Jordan Phillips Date: created: Jun 30 2022
5-fluorouracil (5-FU), capecitabine, floxuridine, cytarabine, gemcitabine, decitabine, and vidaza are some of the significant anticancer drugs in the antimetabolites class that work by interfering with DNA synthesis to cause cytotoxicity.
Asked By: Chase Bryant Date: created: Jan 28 2022
What is the major side effect of alkylating agents
Answered By: Peter Alexander Date: created: Jan 28 2022
Anemia, reduced blood cell counts (pancytopenia), and hair loss (alopecia) are among the most frequent side effects of alkylating agents.
Asked By: Michael Johnson Date: created: Mar 11 2022
What are called antimetabolites
Answered By: Peter Hill Date: created: Mar 12 2022
Because of their structural similarity to natural purine or pyrimidine bases, nucleosides, or nucleotides—molecules required to carry out primary metabolic reactions—antimetabolites are a class of anticancer medications that act as analogues of normal metabolites and disrupt the normal metabolism.
Asked By: Leonars Murphy Date: created: Dec 16 2021
What is the meaning of antimetabolites
Answered By: Howard Sanchez Date: created: Dec 18 2021
(AN-tee-meh-TA-boh-lite) A medication that is remarkably similar to natural chemicals in a typical biochemical reaction in cells, but different enough to impair normal cellular division and function
Asked By: Stanley Martinez Date: created: Oct 07 2021
What are antimetabolites explain with the help of an example
Answered By: Elijah Hernandez Date: created: Oct 08 2021
Other examples include antagonists of purines (azathioprine, mercaptopurine, and thioguanine) and antagonists of pyrimidine (fluorouracil and floxuridine), which interfere with bacterial metabolism but not human metabolism and are used to treat bacterial infections in humans.
Asked By: Daniel Roberts Date: created: Feb 03 2022
How do antimetabolites work
Answered By: Lawrence Bell Date: created: Feb 05 2022
The majority of agents are cell cycle phase specific for S phase and interfere with DNA and RNA synthesis by acting as false metabolites that are incorporated into the DNA strand or block essential enzymes, preventing DNA synthesis.
Asked By: Douglas Moore Date: created: Dec 14 2022
Which are examples of antimetabolites used in chemotherapy
Answered By: Curtis Moore Date: created: Dec 17 2022
Examples of antimetabolites include:
- Azacitidine.
- (5-FU) 5-fluorouracil
- (6-MP) 6-mercaptopurine
- (Xeloda) Capecitabine
- Cladribine.
- Clofarabine.
- Ara-Cs Cytarabine
- Decitabine.
Asked By: Matthew Torres Date: created: Oct 03 2022
What are cytotoxic effects
Answered By: George Lewis Date: created: Oct 06 2022
Once inside the body, they can cause a variety of bioeffects like apoptosis, cell membrane disruption, inflammation, and oxidative stress. These include spontaneous protein adsorption, interaction with cell membranes, DNA, lipids, and proteins.
Asked By: Benjamin Smith Date: created: Nov 12 2021
How do antimetabolites exert their cytotoxic effect
Answered By: Stanley Lee Date: created: Nov 12 2021
Some of the important drugs from this class include 5-fluorouracil (5-FU), capecitabine, floxuridine, cytarabine, gemcitabine, decitabine, and vidaza. Antimetabolites are a group of anticancer agents that interfere with DNA synthesis to produce their cytotoxic effects.
Asked By: Alex Thompson Date: created: Feb 18 2022
What are the adverse effects of methotrexate
Answered By: Douglas Roberts Date: created: Feb 18 2022
Methotrexate may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
- dizziness.
- drowsiness.
- headache.
- swollen and soft gums.
- reduced appetite
- eye redness.
- hair fall
Asked By: Carl Adams Date: created: Oct 24 2021
Which antibiotics are antimetabolites
Answered By: Jesse Walker Date: created: Oct 24 2021
Each monomer unit of DNA and RNA contains either a purine or a pyrimidine as the base, and the most frequently used antimetabolites are methotrexate, trimethoprim, and sulfonamides, which inhibit the synthesis of dTMP, which is a pyrimidine (Sect.
Asked By: Leonars Bennett Date: created: Sep 06 2022
In which phase of the cell cycle do most antimetabolites affect cells
Answered By: Keith Long Date: created: Sep 09 2022
Because they act primarily on cells synthesizing new DNA for the formation of new cells, antimetabolites are most effective during the S-phase of cell division. The toxicities associated with these drugs are seen in cells that are growing and dividing quickly.
Asked By: Samuel Murphy Date: created: Mar 22 2022
Which chemotherapy drug has heart failure as a serious toxicity
Answered By: Dylan Bailey Date: created: Mar 23 2022
The widely used chemotherapy drug doxorubicin may cause heart toxicity, which could result in congestive heart failure, according to recent research.
Asked By: Clifford Stewart Date: created: Jun 05 2022
Which term is used for antimetabolite block the metabolic action of Vitamin causing its deficiency
Answered By: Ralph Lee Date: created: Jun 05 2022
Limitex (Pemetrexed)
Asked By: Jack Lee Date: created: Jan 16 2023
What is toxic mucositis
Answered By: Nicholas Taylor Date: created: Jan 18 2023
Myoo-koh-SY-tis is a side effect of some cancer treatments in which the lining of the digestive system becomes inflamed, frequently manifesting as mouth sores.
Asked By: Leonars Flores Date: created: Oct 09 2021
How does methotrexate make you feel
Answered By: Caleb Bryant Date: created: Oct 11 2021
Up to one-third of rheumatoid arthritis (RA) patients who take methotrexate experience mouth ulcers or sores, and the majority experience GI issues like nausea and vomiting. Other common side effects include headaches, fatigue, and a general feeling of being “blah.”
Asked By: Samuel Wright Date: created: Jul 02 2022
Are antimetabolites steroids
Answered By: Cameron Bailey Date: created: Jul 04 2022
Methotrexate has been shown to be effective in remitting and persistent disease, as well as in ocular, 234, 288 cutaneous, 289 – 291 sinus, 292, and neurologic disease. Methotrexate is a commonly used steroid-sparing cytotoxic agent for sarcoidosis.
Asked By: Lucas Mitchell Date: created: Dec 29 2022
What are antimetabolite immunosuppressant drugs
Answered By: Caleb Lee Date: created: Dec 29 2022
An inosine monophosphate dehydrogenase inhibitor used to prevent the rejection of kidney, heart, or liver transplants. An immunosuppressant used to prevent organ transplant rejections.
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